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Among existing signaling pathways, the mitogen-activated protein kinase (MAPK) and nuclear factor-B (NF-B) signaling pathways are key regulators of inflammatory processes

[DOI] [PMC free article] [PubMed] [Google Scholar] 414.Naessens DMP, de Vos J, Richard E, Wilhelmus MMM, Jongenelen CAM, Scholl ER, van der Wel NN, Heijst JA, Teunissen CE, Strijkers GJ, Coolen BF, VanBavel E, Bakker ENTP

Dietary -6/-3 polyunsaturated fatty acid ratios affect the homeostasis of Th/Treg cells in mice with dextran sulfate sodium-induced colitis

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The agency notes that the peptide is highly susceptible to protein aggregation and the accumulation of peptide-related manufacturing impurities when formulated for injection, which can trigger massive, systemic immune system reactions in human patients

Author Contributions A.S.: original writing