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It also supports the release and synthesis of acetylcholine, as well as enhances the release of dopamine from neurons and helps it bind to dopamine receptors

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Sultan, et al

Hazen et al

According to Kaplan et al., intra-VTA A 1 R agonism suppresses morphines effects on motor activity and VTA projections neural activation, including Fos immunoreactivity in the nucleus accumbens [80]
