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Kagan, V., Serbinova, E

The increased apoptosis with triple therapy (Hi + Ci + G) revealed by TUNEL staining was supported by findings of increased caspase-3 and -9 expression in this group

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Also, patients with ACLF display highly compromised tumor necrosis factor- (TNF-) production and HLA-DR expression under ex vivo conditions (46)

Previous research suggests that SCFAs, particularly butyric acid and propionic acid, may act as signaling molecules that directly or indirectly influence cellular proliferation and anabolic metabolism by modulating key signaling pathways such as mTOR (Frampton et al., 2020)

Dong L, Luo W, Maksym S, Robson SC, Zavialov AV Adenosine deaminase 2 regulates the activation of the toll-like receptor 9 in response to nucleic acids