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Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum

Symptoms of an allergic reaction may include: Itching or rash Hives or welts Difficulty breathing Swelling of the face, lips, or tongue If you experience any signs of an allergic reaction, seek immediate medical care

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These are uncommon but serious, and leg pain that occurs without a clear cause or worsens over time warrants professional evaluation

Generally, single-compartment models assume one volume for alcohol distribution and elimination, such as the Widmark and Wilkinson models (156, 159)
