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A blood test will confirm a deficiency, with typical thresholds being total B12 levels under 180 nanograms per litre or active B12 below 25 pmol/l

Herberts proposed model, illustrating the biochemical, metabolic, and clinical changes that occur as B12 levels move from repletion to depletion, eventually leading to clinical vitamin B12 deficiency: The 4 Stages of B12 Deficiency In Detail Heres a more detailed description of all B12 deficiency stages: Stage 1: Early Serum Depletion This marks the beginning of B12 deficiency

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Taking omeprazole, lansoprazole or other stomach acid-reducing drugs might decrease your bodys ability to absorb vitamin B12

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