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Use of 6-hydroxydopamine to create lesions in catecholamine neurons in rats

Strategies aimed at disrupting lactate-mediated ferroptosis resistance in tumors while reducing lactate-mediated ferroptosis in sepsis may offer selective therapeutic windows

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Native IGF-1 binds IGFBP-3, the dominant carrier protein in circulation, with a dissociation constant in the low nanomolar range (Kd approximately 0.1 to 1 nM in most published binding assays)

Mutat Res 482, 2126 (2001)

Not suitable for standalone affinity purification (anti-Flag columns are costly) best paired with His for a detection + purification dual-tag strategy