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In animal models, researchers measure parameters such as circulating free fatty acids, respiratory exchange ratios, and adipose tissue gene expression to characterize shifts in substrate utilization

Vegans and Vegetarians: Since B12 is primarily found in animal products, those on strict plant-based diets are at a higher risk of deficiency and may need supplementation

[1] Renal function should be monitored if significant gastrointestinal symptoms or dehydration occur

The docket number is FDA-2025-N-6895, and it will remain open until 22 July 2026

Store reconstituted solution refrigerated at 28C and use within 28 days of first puncture

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