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FIGURE 2 3.2 Inflammatory pathway activation via mtROS and mtDNA leakage 3.2.1 mtROS and the NLRP3 inflammasome mtROS is a potent activator of the NLRP3 inflammasome, a multiprotein platform composed of NLRP3, ASC, and caspase-1 (Jang et al., 2015

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doi: 10.1146/annurev.neuro.28.061604.135718

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Briakinumab is a human monoclonal antibody that inhibits the actions of IL-12/23 (Patel 2012

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Autism-like behavioral phenotypes in BTBR T+tf/J mice

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In other words, there are a variety of non-toxic therapies that your son can undergo once his active therapies stop

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