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MMR removes the base opposite to the adduct, which may cause a new mismatch, starting the pathway again and leading to the so-called futile cycle, generating double stranded breaks

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Humic acids (HA) are humus materials that are aqueous-alkaline soluble and have been proposed as a sustainable alternative to alleviate salinity stress and improve plant crop productivity (Elkhatib et al., 2021)

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Ageing exacerbates ribosome pausing to disrupt cotranslational proteostasis

these changes do not make it a growth-hormone secretagogue, instead they sharply reduce its binding to IGF-binding proteins (IGFBPs), which is what extends its circulating half-life and potency relative to native IGF-1