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Under exposure to Tat, cocaine, or ART, lysosomal dysfunction is observed: lysosomal pH rises, lysosome-associated membrane protein 2 (LAMP2) decreases, and cathepsin D decreases

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[DOI] [PMC free article] [PubMed] [Google Scholar] 110.Nishimura Y, Kanda Y, Sone H, Aoyama H

Pathology and biology of the lewy body

Fingert et al., 2017)

Neutrophils, macrophages and PBMCs from SARS-CoV-2-infected patients also exhibited active AIM2 or NLRP3 inflammasomes and enhanced expression of ASC-speck protein, caspase 1 or gasdermin-D (199, 221, 233)