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This means millions of people are living with a condition that can cause everything from crippling fatigue to irreversible damage to the brain and nervous system if left untreated

Barton M, Haudenschild CC, d'Uscio LV, Shaw S, Mnter K, Lscher TF

Oxidative stress and Mitotracker staining assays were performed by Laboratory 1 only, whereas tissues material exposure for high-throughput transcriptomics analysis was performed by Laboratory 2

In each case, the damaged mRNA leads to decreased gene expression

J Cell Biol 178: 93105 Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB et al (2008) Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

doi: 10.1080/09553000110104065
