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This suggests that a significant proportion of dietary polyphenols are expected to reach the colon where they may interact with the gut microbiome 7881

Collectively, these findings suggest that ER in the brainstem, and specifically the NTS, is an additional site mediating the anorexigenic effects of estrogens

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Sulforaphane activates a genetic pathway called Nrf2, which turns on the Phase II detoxification enzymes your liver uses to package estrogen metabolites for elimination [17, 18]

Bae, J.-H., Song, D.-K