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Companies choose Paragraph III when they judge that the listed patent is robust enough that a Paragraph IV challenge is unlikely to succeed, when the commercial value does not justify the litigation cost, or when they want to queue up an approval that will be immediately effective on the expiration date

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Dietary supplementation of natural antioxidant compounds derived from plants has been much discussed in the literature

doi: 10.1038/s41467-022-33415-5 305 Castro-MarreroJZacaresMAlmenar-PrezEAlegre-MartnJOltraE

Long-chain saturated free fatty acids (FFAs) produced by reactive astrocytes promote OL death in culture 116