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The longer answer involves understanding why copper peptides became injectable in the first place, what the research actually shows about topical delivery, and why needles might be solving a problem that doesn't exist for most people

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Taking injections with food and staying well-hydrated can help reduce this effect

[DOI] [PubMed] [Google Scholar] Castelli MC, Wong D, Friedman K, Bhargava P, Riley GM

In cartilage biology research, investigators have observed that AOD9604 is associated with proteoglycan synthesis in chondrocyte models, suggesting potential activity in extracellular matrix maintenance