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L-carnitine and creatine in Friedreichs ataxia

52 : 8994 Pettegrew JW, Klunk WE, Kanal E, Panchalingam K, McClure RJ

An open-label, non-randomized trial in 69 patients with either type 1 or type 2 diabetes mellitus found a reduction in the incidence of muscle cramps and an improvement in the quality of life of those prescribed 0.6 g/day of L-carnitine for four months compared to controls (127)

Transparent Labs says that they omit creatine because caffeine blunts its effects when taken together, but research on that topic is scarce and inconclusive