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Andrew: I think of the millions of people that suffer from lack of rapid eye movement sleep, the lack of neuroplasticity that can be the consequence of that, the lack of healthy removal of emotional labels on previous day memories, that is the consequence of REM deprivation

Notably, the versatility of the key regulators of mitochondrial biogenesis (PGC1, NRF2) and mitophagy (Parkin) may further underline that these two processes are balanced and constrained with each other in order to control mitochondrial function under multiple physiological conditions

A focus on patient safety ensures that data generated are dependable and that any potential risks are proactively managed, leading to more favorable outcomes in pivotal studies

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