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Nrf2 is well known for mediating the expression of antioxidant and detoxifying proteins in response to oxidative and electrophilic stress (reviewed in [162, 163])

doi: 10.1007/s12024-015-9737-x 122 LeH-YTienNDSonPNViet HoaLTPhuongLLHaiPD

Free Radic Biol Med 37, 937945
doi: 10.1097/01.psy.0000195780.37277.2a 141 Sowa-KumaMStyczeKSiwekMMisztakPNowakRJDudekDet al

33.Ducker G.S., Rabinowitz J.D
Nonetheless, the potential drawbacks include unresolved concerns about drug interactions between existing antineoplastic drugs and anti-DTP, as well as the hepatic and renal loads resulting from the combined metabolism of the two drugs
