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deficient glutamate clearance is the primary element of several severe neurodegenerative diseases such as for example in ALS, 144,145 and Wernickes encephalopathy 146

Reducing agents : Compounds that possess lower redox potential than the oxidation substrate in the formulation, thereby acting as a reduc-ing agent by getting preferentially oxidized

26,160 Subsequently, the final phase of tissue remodelling plasticity starts

[DOI] [PubMed] [Google Scholar] Tsuruwaka, Y

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Despite advances in chemotherapy, radiotherapy, and targeted therapies, challenges such as poor drug accumulation, systemic toxicity, and multidrug resistance persist, partly due to elevated intracellular GSH levels that neutralize reactive therapeutics and reduce treatment response