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To investigate, whether PTC-3 shares the function of PTCH1 as cholesterol transporter, we first expressed PTC-3 in Saccharomyces cerevisiae , which does not contain any cholesterol 31 and measured cholesterol efflux from cells using TopFluor cholesterol in a pulse-chase experiment (Fig
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It is therefore unsurprising that microbiota-derived metabolites can directly impact the phenotype and function of these cells (Fig
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MDA has been widely used in biomedical research as a marker of lipid peroxidation due to its facile reaction with thiobarbituric acid (TBA)
