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Capmatinib is an ATP-competitive and highly selective small molecule c-MET receptor TKI that demonstrated inhibition of MET activation in cancer cells whose growth is driven by MET amplification, MET overexpression, MET exon 14 skipping mutations, and HGF-mediated activation (Baltschukat et al., 2019)

Nevertheless, ISF primarily supports the detection of small and moderately sized molecules

L-DOPA, as a dopamine precursor, remains the most effective medication for PD [99]

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