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Furthermore, immune-mediated pathways, including sclerostin inhibition of Wnt signaling and FGF-23 dysregulation, have emerged as critical regulators of mineral metabolism and potential therapeutic targets beyond conventional phosphate management (123, 124)

Tang et al., Reference Tang, Zhao, Yang, Wang, Li, Kleist, Lemaux and Luan2020)

To assess the activity of ascorbate peroxidase enzyme (APX), 2 mL of 0.05 M phosphate buffer, 0.2 mL of 3% hydrogen peroxide, and 0.2 mL of 50 M ascorbate were mixed in an ice bath (04 C), and immediately, 100 L of enzyme extract was added

doi: 10.1681/ASN.2014070698

RC: Writing review & editing, Supervision, Resources, Funding acquisition, Conceptualization