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In sepsis, the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system are the two main pathways of neuromodulation (57)

[DOI] [PubMed] [Google Scholar] 97.Tth K., dm D., Br T., Olh A

However, other sequences provide additional information likely to be relevant in PD

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By properly balancing endothelial nitric oxide synthase (eNOS) and inducible nitric oxide synthase (iNOS) signaling, BPC-157 down-regulates destructive pro-inflammatory cytokines without neutralizing the acute, necessary oxidative signals needed to command cellular division 6

doi: 10.1111/j.1365-2109.2008.01932.x