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These include downregulation of sGC and upregulation of phosphodiesterase activity

BLI BLI kinetic experiments were performed using an OctetRED96 instrument from PALL/ForteBio

Fatalities and serious adverse reactions, including severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), acute febrile neutrophilic dermatosis (AFND), acute generalized erythematous pustulosis (AGEP)

Months 1-2: Foundation Establishment (As Described Above) The initial two months mirror the three-month protocol's foundation phase, establishing baseline responses and optimizing protocols for individual needs

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