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The transcription factor IRF7 is upregulated in colitis and represses the transcription of miR-375-3p
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This gel-like mucosal barrier serves as a primary defense mechanism by competitively inhibiting the adhesion of pathogenic bacteria to host surfaces ( Specific molecular mechanisms underlie this process
doi: 10.1046/j.1471-4159.1999.0730889.x 53
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