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The protective effects of GSH include the neutralization of oxygen radicals, the maintenance of mitochondria and mitochondrial DNA, the chelation of heavy metals such as mercury, the regeneration of vitamins C and E, the regulation of apoptotic pathways, and action as a cofactor for antioxidant enzymes [20]

GR activity was calculated using the equation below

CNS Drugs 2007;21(1): 1-11

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91,92 This can be affected by diseases of the intestinal mucosa as well as pancreatic disease, as the carrier protein, intrinsic factor, only comes from the pancreas in cats