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Description
The UPR regulates mitochondrial activity at several levels, including enhancing mitochondrial protein quality control, augmenting ER-mitochondrial interactions and calcium signaling, and contributing to mitochondrial depolarization and initiation of apoptosis (Fan and Simmen, 2019, Gutierrez and Simmen, 2018, Rainbolt et al., 2014)
doi: 10.1016/j.freeradbiomed.2020.02.027
F.CoppoL
4a), which catabolizes GSH to yield 5-oxoproline and cysteinylglycine (Cys-Gly) 42
Gelperin, D.M
Pediatrics 2015;135:e918e926
