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This was also supported by the clinical evidence where vitiligo patients found gut dysbiosis with reduced Bacteroides compared to the healthy controls [191]

These effects were accompanied by enhanced hepatic fatty acid catabolism and a reduction in the tissue n-6/n-3 PUFA ratio, underscoring the role of n-3 PUFAs in counteracting chronic TNF-driven inflammation and metabolic dysfunction ( Beyond general inflammation, EPA has also demonstrated a targeted ability to inhibit specific pro-tumorigenic pathways

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doi: 10.3389/fnmol.2023.1267343 60 MombereauCKaupmannKFroestlWSansigGvan der PuttenHCryanJF

50 (D1), D622D631 (2022)