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During periods of stress or fasting epinephrine and glucagon function in a concerted manner to maximally stimulate hepatic glycogen breakdown and gluconeogenesis

Experimental animals demonstrated rather marked changes in the activities of the antioxidant enzymes SOD and CAT in their liver and brain cells, and changes in the levels of GSH and MDA were observed when compared with the control group

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Reactive oxygen species (ROS) may mediate mitochondrial stress and are closely associated with tight junction protein expression and MMP activation

K.LundJ

10.1007/s00586-006-0171-3 Eur