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This disruption severely affects cochlear energy metabolism and enhances susceptibility to further ototoxic damage

Gleason et al., 2009)
Greater methylation potential, as shown by greater SAM/SAH ratios, was also linked with better cognitive abilities (Obeid et al., 2009)

SHBG is a transport protein that binds sex hormones in the blood
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Eirin A, Lerman A, Lerman LO (2017) The emerging role of mitochondrial targeting in kidney disease