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doi: 10.1038/nrn3961
Surprisingly, native LDL is not taken up by macrophages in vitro but has to be modified to promote foam cell formation
This dysfunction leads to the loss of metabolic support (e.g., GLT1 downregulation) and the secretion of pro-inflammatory cytokines such as IL-1, TNF, and IL-6
A., Perlmutter, D
The total number of individuals with diabetes is projected to increase from 171 million in 2000 to 366 million by 2030 [104]
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