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Soluble oligomeric A has been shown to induce oxidative stress and has been proposed to play a central role in the oxidative damage detected in AD brain (Xu et al., 2014)
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Gene constructs were designed using benchling (above) and basic parts making up transcriptional units (below)

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8a, both Grx1 and Grx2 expression levels were reduced in livers from HFD-fed mice compared to control mice