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Absorption requires intrinsic factor from gastric parietal cells and occurs in the terminal ileum, though high oral doses (1,0002,000 micrograms) can bypass this mechanism through passive diffusion

however, 3 were ineligible due to 1 not being resistance-trained and 2 had previously taken nutritional supplements that were included in the exclusionary criteria

32 (suppl 2)

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Specifically, the researchers suggested that the cleavage of caspase-3 and its substrate called Poly ADP-ribose polymerase (PARP) appeared markedly reduced, by ~43% and ~77% respectively, suggesting that the peptide complex may suppress this cascade of programmed cell death

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