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Measurement of glutamate Cells were collected in phosphate buffer (100 mM sodium phosphate, 1 mM ethylene diamine tetraacetate, pH 7.5) and sonicated and lysates centrifuged to remove insoluble debris

The hypothesis that CYP2E1 modulates myocardial pathologies via mitochondrial biological processes was tested through transcriptomic and proteomic analyses using CYP2E1-specific animal models and stable H9c2 cell lines overexpressing Flag-CYP2E1 (Fig

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