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A specific role for IGF-1 receptor (IGF-1R) signaling in the mediation of mammalian longevity was first established in IGF-1R haploinsufficient mice, which lived 33% longer than controls, but unlike other models of reduced somatotropic signaling, this effect was female specific 6

Early data suggests BPC-157 may help maintain a healthy gut lining and support the repair of irritated or damaged gastrointestinal tissue

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See the Melanotan II peptide profile for receptor detail

Hormone replacement therapy attenuates hearing loss: mechanisms involving estrogen and the IGF-1 pathway