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[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Santos L., Tomatis F., Ferreira H.R.S., Almeida S.F.F., Ciputra E., Sereno J., Almeida R., Teixeira P., Ribeiro A.S., Moreira J.N., et al

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In hepatocellular carcinoma (HCC) cells, post-translational activation of cystathionine -synthase (CBS) under TNF-induced oxidative stress increases TSS activity through a proteolytically cleaved and highly active form of CBS, increasing cystathionine and GSH production (102), which in turn promotes tumor progression and inhibits ferroptosis