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However, the subchondral bone thickness was decreased in Igf1 CART-KO mice upon Wnt activation but not in control mice (Supplementary Fig

Subsequent cell culture studies revealed that GSSG accumulation, as opposed to GSH reduction, sensitized hepatocytes to TNF killing by reducing the TNF-triggered NF-B activity

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Glutathione participates in various physiological processes involved in redox reactions by serving as an electron donor/acceptor

For instance, 2-DG synergizes with Etoposide to increase cytotoxicity, promote tumor-specific T-cell activation, and induce immunogenic cell death

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