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Review of pramlintide as adjunctive therapy in treatment of type 1 and type 2 diabetes

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However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007

[DOI] [PubMed] [Google Scholar] 128.Neary MT, Batterham RL