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Both peptides require slow dose escalation in clinical protocols, primarily to mitigate gastrointestinal adverse effects

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Both are susceptible to oxidation, especially in aqueous solutions and at higher temperatures

It accelerates re-epithelialization, supports stem cell differentiation, and improves recovery in aged or damaged tissues through increased microvessel density and modulated inflammatory pathways (e.g., NF-B and MAPK)

The needle size and injection site, together, help reduce the pain and discomfort of administration