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Cytotoxicity Assay The assessment of the hepatoprotective effect of SAG was performed using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) reduction assay [42]
Metformin is found to down-regulate cellular FADD-like IL-1-converting enzyme (FLICE)-inhibitory protein (c-FLIP) and markedly enhance autophagic flux, ultimately facilitates apoptosis triggered by TRAIL [91]
doi: 10.1016/S1875-5364(14)60009-1 23 ZhangJIpFCFLiangYIpNYZhongB-LLaiC-Wet al
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