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A responder analysis found about 65% of children on leucovorin had a notable language improvement , versus only 24% on placebo

Prolonged and unregulated use could also impact hormonal balance, potentially leading to adverse effects on thyroid function and natural growth hormone production

Dietary glutathione intake in humans and the relationship between intake and plasma total glutathione level

doi: 10.1016/j.ejphar.2014.01.046

J Pediatr Pharmacol Ther 19

Risks: Slower and less effective compared to injections
