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However, IL-15-mediated upregulation of ZO-1 and ZO-2 expression was independent of the IL-2R subunit, whereas phosphorylation of occludin and enhanced membrane association of claudin-1 and claudin-2 by IL-15 required the presence of the IL-2R subunit
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67 Marked elevations of D-dimer have been observed in sepsis, demonstrating the prognostic importance of D-dimer in relation to the severity of the patients condition
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These effects were abolished by treatment with NG-L-monomethyl arginine, a specific inhibitor of NO synthase
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