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Elsberry VA, Grangeia JM, Giorgianni SJ et al

One notable example of drug development pipelines influenced by preclinical findings include the advancement of elamipretide, a peptide designed to stabilize mitochondrial membranes, which showed efficacy in preclinical models of Barth syndrome and Primary Mitochondrial Myopathy and subsequently progressed to clinical trials (Sabbah, 2022

In the cancer cell-DRG coculture system, the cancer cell invasion index and DRG axon growth index, which were inhibited by knockdown of mTOR expression, were recovered by HGF (Fig

18 , 375384.e1 (2020)

Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis

In line with these studies, we also proved significantly higher activity of GPx in HAEA-treated groups
