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25 Forest plot of the sperm DNA fragmentation in infertile patients treated with antioxidants (AOXs) compared to placebo or untreated infertile controls, after the removal of studies including patients with varicocele undergoing varicocele repair

instead Nrf1 is primarily localized to the membrane of the endoplasmic reticulum and is released and translocates to the nucleus during endoplasmic reticulum stress [113]