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Although long-term endurance training and the late recovery phase after acute bouts tend to promote M2-like macrophage polarization, the early phase following acute exercise is dominated by the mobilization of pro-inflammatory monocytes and an increase in M1-like macrophage infiltration, particularly in skeletal muscle tissues (3941)

Oncol rep 2015;33:2121-8

Activated VSMCs migrate to the intima, further exacerbating inflammation, oxidative stress, and the deposition of collagen and elastin proteins in the fibrous cap (198)

PMID: 62 WangS.MaQ.LiC.ZhangS.LiuX

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Circadian misalignment induced by disrupted lightdark cycles or genetic loss of NRF2 contributes to ROS accumulation and impaired activity of NRF2 and its target genes, including GCLC, GCLM, and Prdx3 (Lee et al