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Indeed, the PDH complex, which decarboxylates glycolytically derived pyruvate to acetyl coenzyme A and links cytoplasmic glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle, is modulated by reversible phosphorylation by PDH kinase (PDK)

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Rare presentation of a treatable disorder: glutaric aciduria type 1

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In the presence of reactive oxygen species, uric acid is metabolized by urate oxidase to allantoin in non-primate mammals [61], and may be considered indicative of increased oxidative stress in ruminants [62]
