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Reson Imaging 6 (1), 162166
Moreover, FXR knockout mice exhibited increased levels of BAs in serum and brain tissue, along with disruption in neurotransmitter pathways in different brain regions 53
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Nature (2007) 447(7146):8648
This results in the involvement of all of the polar groups of the molecule in the hydrogen bonding, so that none are available for hydration
