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To conduct this review, a systematic literature search was performed, covering studies published in English between 2020 and 2024, using databases such as PubMedPico, Scopus and Web of Science, with keywords such as hesperidin, SARS-CoV-2, COVID-19 and antiviral agents

Furthermore, the more recent observational data suggesting that the combination of high folate and low vitamin B-12 is associated with the worsening of both clinical outcomes and elevations in functional biomarkers of vitamin B-12 (23, 40, 41) imply that depletion of holoTC is attained even without stimulating hematopoiesis

The gut contributes to the maintenance of the defense and repairs the gastrointestinal mucosa [33]

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The liver chemically transforms toxins, drugs, pesticides, mycotoxins, plasticizers, PFAS, flame-retardants, and metabolic byproducts into forms that can be excreted