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Author Contributions MNA contributed to conceptualization

Core components of these pathways, including AKT1 and TNF, have emerged as potential targets for therapeutic intervention [449]

10.1016/j.freeradbiomed.2008.08.014 Free Radic Biol Med

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Phase 2 trial data showing up to 24% body weight reduction over 48 weeks put it ahead of every approved therapy currently on the market

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