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The viral hijack of human ACE2 receptor disrupts RAAS activation, upregulates NF-B pathway, triggers cytokine storm, hypertension, cell proliferation, inflammation, and fibrosis, where all elicit detrimental effects on every bodily organ during SARS-CoV-2 infection 635

[DOI] [PubMed] [Google Scholar] 100.Williamson G., Kay C.D., Crozier A

doi:10.1038/ng.2982

Specifically, donepezil and galantamine rarely induce EPS signs when taken alone

Sulforaphane (SFN) is a natural isothiocyanate present in a variety of vegetables [242], which can target Nrf2 and has potential anti-cancer activity [243]

The targets B-cell lymphoma-2 (Bcl-2) and Superoxide dismutase (SOD2) were finally obtained (Figure 3B)
