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Further research is needed to establish standardized protocols for PRP administration and identify patients most likely to benefit from this treatment

doi: 10.1016/j.csbj.2021.01.034 53 BhandoolaASambandamA

Intramuscular injections typically produce early haematological responses within 34 days, whilst neurological symptoms may begin improving within 12 weeks

They represent a carefully identified sequence from a larger protein called Body Protection Compound, which the human stomach produces naturally as part of its protective mechanisms

This is because while methotrexate helps to decrease swelling in your joints, Prolia helps to decrease joint damage from RA

But I could be wrong